Termination of appointment of Stuart Wilson Lewis as a director on 26/04/2016

Termination of appointment of Sherry Leigh Coutu as a director on 26/04/2016

Termination of appointment of Sharon Margaret Bowles as a director on 26/04/2016

Annual return made up to 18/02/2016 no member list

Appointment of Mr David Thomas Nish as a director on 04/12/2015

Appointment of Dr Leonard Hubertus Hoogduin as a director on 04/12/2015

Statement of capital following an allotment of shares on 01/09/2015 GBP 26,443,069.339959

Statement of capital following an allotment of shares on 05/08/2015 GBP 26,417,151.31

Statement of capital following an allotment of shares on 08/07/2015 GBP 26,306,765.34

Termination of appointment of Massimo Tononi as a director on 07/08/2015

Statement of capital following an allotment of shares on 17/06/2015 GBP 26,303,891.21

Statement of capital following an allotment of shares on 10/06/2015 GBP 26,234,705.16

Appointment of Mary Schapiro as a director on 01/07/2015

Termination of appointment of Christopher Shaw Gibson Smith as a director on 01/07/2015

Appointment of Mr Donald Hood Brydon as a director on 19/06/2015

Statement of capital following an allotment of shares on 12/05/2015 GBP 26,037,231.22

Statement of capital following an allotment of shares on 15/04/2015 GBP 25,834,895.53

Termination of appointment of Joanna Shields as a director on 19/05/2015

Statement of capital following an allotment of shares on 18/03/2015 GBP 25,684,192.62

Group of companies' accounts made up to 31/12/2014